NeuroImaging Nowadays in multiple sclerosis (MS) 

• Provide a unique learning and training experience in MS and other demyelinating diseases and Neuroimaging
• Foster knowledge on MS diagnosis and differential diagnosis, disease monitoring, prediction of treatment response, and assessment of treatment efficacy & safety
• Empower Neurologists, Neuroradiologists, Radiologists and Residents with an interest in MRI and MS

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Multiple sclerosis (MS) is a chronic autoimmune demyelinating inflammatory and degenerative disease of the central nervous system, characterized by the presence of inflammatory lesions in the brain and spinal cord. It is most commonly diagnosed in people in their 20s and 30s, although it can develop at any age. It is about 2 to 3 times more common in women than men. To diagnose multiple sclerosis and evaluate the progression of the disease, magnetic resonance imaging is often the most reliable test because of its high sensibility and specificity in detecting demyelinating lesions. It also allows for differential diagnosis and assessment of the response to the therapeutic.

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Module 1 | MRI and the diagnosis of MS 

• Overview of MRI in MS
• Conventional MRI techniques
• Current diagnostic criteria: 2017 Revised McDonald criteria

Christian Enzinger, Austria - Lina Savsek, Slovenia

Module 2 | MRI and MS monitoring: disease activity and progression

• Brain MRI for MS treatment efficacy monitoring
• Brain MRI for MS prognosis
• Brain MRI for MS safety monitoring

Cristina Granziera, Switzerland - Mike Wattjes, Germany

Module 3 | MRI and multiple sclerosis misdiagnosis and differential diagnosis: Pearls and oyster

• Reasons for misdiagnosis of MS
• McDonald 2017 - focus on specificity
• Red flags on imaging: MS mimics

Mike Wattjes, Germany

Module 4 | Radiologists and Neurologists: chances and challenges in communicating in current times

• How to improve communication between neurology and radiology? Moving things forward
• Standards in reporting of the neurological exam 
• best and worst practice examples

Alex Rovira, Spain - Jan Casselman, Belgium - Melissa Cambron, Belgium - Jaume Sastre-Garriga, Spain

Module 5 | The role of spinal cord in MRI: diagnosing, monitoring and predicting treatment response in MS

• Value of spinal cord MRI
• Standardize spinal cord image acquisition
• Spinal cord MRI: diagnosis, differential diagnosis and treatment monitoring

Jiwon Oh, Canada - David K. B. Li, Canada

Module 6 | Optic Nerve MRI And Optical Coherence Tomography (OCT)

• Value of optic nerve MRI
• Role of OCT in MS
• Correlations between brain or optic nerve adnormalities on MRI, and retinal pathology using OCT

Hugh Kearney, Ireland - Axel Petzold, UK

Module 7 | MRI features of specific MS populations and other CNS inflammatory diseases

• Pediatric MS
• Elderly MS patients
• Pregnancy and Breastfeeding in women with MS
• Atypical Demyelination
• Intricacies of progressive vs. relapsing MS

Thomas Berger, Austria - Kerstin Hellwig , Germany - Christian Enzinger, Austria - Klaus Schmierer, UK

Module 8 | Brain and spinal cord atrophy in clinical practice: evidence and barriers to implementation

• Physiological atrophy & clinical relevance of volume changes in patients with MS
• Value of volume changes to predict treatment response in patients with MS
• Atrophy in clinical practice: evidence and barriers to implementation

Jožef Magdič, Slovenia  - Jaume Sastre-Garriga, Spain 

Module 9 | Neuroimaging and MS: future prospects 

• Neuroimaging and MS: MS future prospects
• MRI and MS: future challenges and developments
• Neuronal repair and remyelination: from biology to therapy
• Advanced and emerging MRI techniques
• Other neuroimaging techniques
• Big data and deep learning: new avenues for MRI research in MS?

Pedro Abreu, Portugal - Daniela Jardim Pereira, Portugal - Stéphane Kremer & Jérôme De Sèze, France - João Duarte, Portugal - Cristina Granziera, Switzerland

Christian Enzinger, MD, MBA, FEAN

Neurologist

Dept. of Neurology Medical University of Graz, Austria

Daniela Jardim Pereira, MD

Neuroradiologist

Coimbra Hospital and Universitary Centre, Coimbra, Portugal

Pedro Abreu, MD

Neurologist

University Hospital Center of São João, Porto, Portugal

Moke Wattjes, MD, PHD

Neuroradiologist

Hannover Medical School, Germany

Thomas Berger, MD, MSc, FEAN

Neurologist

Dept. of Neurology, Medical University of Vienna, Austria

Uroš Rot, MD, PhD

Neurologist

University Medical Centre Ljubljana and Faculty of Medicine, University of Ljubljana, Slovenia